Dosing

Cumulative iron deficit [mg] =
body weight [kg] x (Target Hb – Actual Hb) [g/dL] x 2.4 + iron storage depot [mg]

Dilution and Preparation

This calculator cannot be used to accurately calculate dosage for patients less than 40kg.

Target Hb for body weight below 35 kg = 13 g/dL.Target Hb for body weight 35 kg and above = 15 g/dL.

To convert Hb [mM] to Hb [g/dL]: multiply Hb [mM] by the factor 1.61145.

Factor 2.4 = 0.0034 x 0.07 x 10000;
0.0034: iron content of haemoglobin = 0.34%;
0.07: blood volume = 7% of body weight;
10000: conversion factor 1 g/dL = 10000 mg/L.

Depot iron for body weight below 35 kg = 15 mg/kg body weight. Depot iron for body weight 35 kg and above = 500 mg. This has been allowed for in the calculation.

Doses are rounded down to nearest 100 mg for patients ≤ 66 kg and rounded up to nearest 100 mg for patients > 66 kg.

Administration

Administration times

Maximum dose

Optional supporting tools

It is not possible to draw up the entire contents of the vial into the syringe. A small amount of Ferinject® will remain in every vial. This amount is normal and is accounted for in the filling process.

Therapeutic Drug Monitoring

Administration

Maximum dose

Optional supporting tools

It is not possible to draw up the entire contents of the vial into the syringe. A small amount of Ferinject® will remain in every vial. This amount is normal and is accounted for in the filling process.

Pre-Medication

A maximum single iron dose must not exceed 15 mg iron/kg body weight/week. Do not administer 20 ml (1000 mg of iron) as an infusion more than once a week.

Concomitant Medications

Ferinject® is available in 10ml vials and 2ml vials. This represents 500mg of iron/vial(50mg iron/ml) and 100mg of iron/vial(50mg iron/ml) respectively.

The calculator factors in the wholesale pricing ratio of the vials to give you the best value combination.

Available Vial Sizes

Ferinject® is available in 10ml vials and 2ml vials. This represents 500mg of iron/vial(50mg iron/ml) and 100mg of iron/vial(50mg iron/ml) respectively.

The calculator factors in the wholesale pricing ratio of the vials to give you the best value combination.

PBS and Product Information

PBS Information: Busulfex is not listed on the PBS.

Please review the full Product Information before prescribing, available here.